CD80 and cancer: We found that LLC cancers treated with I + C exhibited a significant increase in the local presence of activated DCs expressing CD11c and CD80 (Fig. 6A, B, Fig. S5A) but no change in the local presence of classic macrophages (M1) (Fig. S5B), alternative macrophages (M2) (Fig. S5C), activated NK cells (Fig. S5D), activated NKT cells (Fig. S5E), or MDSCs (Fig. S5F).