To further determine whether the impaired anti-helminth responses in IEC-KO mice were due to defective IEC STAT6 activity, we infected WT, TgSTAT6vt, IEC-KO, IEC-KO-TgSTAT6vt mice with H. poly and analyzed epithelial responses and worm burden in these mice on day 14 after infection. This evidence concerns the gene STAT6 and infection.