SMYD3 and diffuse large B-cell lymphoma: To further explore the functional role of SMYD3 in DLBCL, RNA-Seq was carried out on total RNA isolated from stable SMYD3-knockdown OCI-LY8 cells transfected with two independent shRNA (shSMYD3 #1 and shSMYD3 #2) and the negative control (NC)OCI-LY8cells.