FBP1 and hepatocellular carcinoma: Hidenari et al. [44] demonstrated that ectopic FBP1 overexpression inhibited tumor growth and intracellular glucose uptake by reducing aerobic glycolysis in hepatocellular carcinoma cells (HCCs), and also found that KEGG- Glycolysis-Gluconeogenesis was enriched in HCCs expressing high levels of FBP1, which indicated the normal glucose metabolism.