Our analysis of the TCGA and GTXs data also showed that FOXD1 expression was higher in PC tissues than in non-tumor tissues (Fig. 1D) and that FOXD1 expression-related genes were significantly enriched in a number of pathways, namely PATHWAY_IN_CANCER, PANCREATIC_CANCER, and GLYCOLYSIS_ GLUCONEOGENESIS (Fig. 1E). This evidence concerns the gene FOXD1 and pachyonychia congenita.