However, the expression of Ki-67 was significantly upregulated in verrucous divided nevus of the eyelids compared with the divided nevus without verrucous hyperplasia, with an average rate of approximately 38.8% in verrucous and approximately 18.3% in non-verrucous nevus, with a significant statistical difference (P < 0.05). The gene discussed is MKI67; the disease is nevus.