The results from the same calculations in the GSE17895, GSE53537, GSE73731, and GSE40435 datasets revealed that SCG2 was significantly over-expressed in patients with ccRCC and the higher the histological grade and pathological stage, the higher the expression of SCG2 (Supplementary Figure 2G–2K). Here, SCG2 is linked to nonpapillary renal cell carcinoma.