ACE and type 2 diabetes mellitus: Post hoc removal of their study from the analysis reduced the sugar subgroup heterogeneity from I2 = 90% (P < 0.0001) to I2 = 68% (P = 0.08), and Cmax in the Asp/Ace-K group compared with the sugar subgroup was not significantly different (MD: –0.63 mmol/L; 95% CI: –1.82, 0.55 mmol/L; P = 0.3; see Supplemental Figure 3), suggesting that Asp/Ace-K blends and sucrose may have similar effects on blood glucose Cmax in healthy individuals but not in those with T2DM.