In conclusion, SNORA70E, which is highly expressed in ovarian cancer, regulates RAP1B mRNA through pseudouracil modification, affecting its protein expression, and further regulates β‐catenin, PI3K, AKT1, and mTOR pathways to promote the development of ovarian cancer and epithelial ovarian cancer tumorigenesis and progression. This evidence concerns the gene AKT1 and ovarian cancer.