CREB1 and breast cancer: However, a role for insulin‐like growth factor 1 receptor (IGF1‐R)/PI3K/AKT and ERBB2/ERK/CREB signaling in the control of FOXA1 expression in BC cells [37, 38], as well as in the ability of FOXA1 to control IGF‐1R expression [38], has been previously reported.