As shown in Table 3, multivariate analyses including other validated prognostic factors (such as tumour grade, lymph node, tumour shape, metastasis stage) and ATM expression (OS; p = 0.003, Hazard ratio = 0.343, 95% CI = 0.171–0.689, DFS; p = 0.003, Hazard ratio = 0.298, 95% CI = 0.134–0.667) independently predicted poor clinical outcome. The gene discussed is ATM; the disease is neoplasm.