The analysis, through a c-bioportal interface [26, 27], showed that NLGN1 expression is very low or absent in almost all cell lines, except in 7 of these (NCI-H716, MDST8, SNU-C2A, COLO320DM, HuTu 80, SNU-175, SNU-503) that we labelled as “NLGN1 upregulated CRC cells” (Fig. 2A). This evidence concerns the gene NLGN1 and colorectal carcinoma.