GTPBP3 and glaucoma: This study demonstrated that taurine can protect R28 cells under glaucomatous injury in vitro (oxidative stress induced by H2O2 and H/R-induced damage, which mimics the ischemia/reperfusion condition in glaucoma (Kim and Byzova 2014)) and explored a new mechanism of the neuroprotective effects of taurine, which depend on the GTPBP3-mediated taurine modification of mt-tRNAs and the promotion of mitochondrial energy metabolism.