As deregulation of Wnt1 activity was associated with various cancers and other human diseases8,9, a meta-analysis was also carried out to assess the overall survival rate of breast, gastric, lungs and ovarian cancer patients with Wnt1 expression, using Kaplan–Meier plotter (Fig. 6); and we found a strong relation between Wnt1 deregulation and the overall survival rate72. This evidence concerns the gene WNT1 and ovarian carcinoma.