Next, we characterized LPXN and PTK2B expression by total proteome analyses in two FLT3-mutated (MV4-11, MOLM-13) and four FLT3-wildtype (Kasumi-1, HL60, OCI-AML2, and OCI-AML3) AML cell lines. The gene discussed is RUNX3; the disease is acute myeloid leukemia.