Furthermore, we demonstrated an increase in TGFβ-R1 and TGFβ-R2 expression at the plasma membrane by flow cytometry analysis of breast cancer cells with suppressed Elovl5 expression (Fig. 4E and Supplementary Fig. S4C) while stable overexpression of Elovl5 reduced their exposure at the plasma membrane (Supplementary Fig. S4D). The gene discussed is ELOVL5; the disease is breast carcinoma.