PDE10A and Onset: Speech difficulties included dysarthria (all HMD genes), language delay (infantile‐onset DDC‐, ATP1A3‐, FOXG1‐, GNAO1‐, PDE10A‐, SLC6A3‐, and TH‐related HMDs), bradylalia (neurotransmitters defects), and dysphonia (KMT2B).