GPT and heart failure: In the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) program, alkaline phosphatase (ALP) was elevated in 14.0% of patients, total bilirubin in 13.0%, alanine aminotransferase (ALT) in 3.1%, and aspartate aminotransferase (AST) in 4.1% of patients.10