Furthermore, the correlation between MMSE and AD‐tau scores for HCs with an MMSE score ≤29 and MCI alone (t[35] = −6.62; rs − 0.75; P < 0.0001) (Table S3) and the lack of correlation in HCs with an MMSE score ≤29 (t[23] = 0.35; rs − 0.19; P = 0.35) or all HCs (t[48] = −1.11; rs − 0.15; P = 0.27) suggest that AD‐tau scores can be used to measure disease severity from HC to MCI and is also important for discriminating between the AD continuum and HCs. The gene discussed is MAPT; the disease is Alzheimer disease.