LCN2 and infection: To address the possibility that Lcn2 may impact the outcome of infection independent of controlling bacterial burdens during bacteremia, and to determine the impact of Lcn2 expression during an acute sublethal infection, we increased the inoculum used to infect the WT and Lcn2-deficient mice from 2 x 108–5 x 108 CFU, to 2 x 109 CFU (~1 log increase).