The results showed that c‐MYC overexpression partially rescued the inhibitory effects of either GAS2 silencing or CXCR4 silencing (Fig. 6), which indicated that the GAS2/CXCR4 axis partially modulated the growth of T‐ALL cells through NOTCH/c‐MYC signaling. Here, GAS2 is linked to acute lymphoblastic leukemia.