Importantly, the transcript expression of GAS2 correlated well with the DNA methylation content in GAS2 promoter region (P = 0.02, R = 0.5), suggesting that hypomethylation in the promoter region of GAS2 plays a role in the aberrant expression of GAS2 in T‐ALL cells (Fig. 1C). Here, GAS2 is linked to acute lymphoblastic leukemia.