The median IL-6 level in HPV-positive patients was 3.40 (2.40–4.40) pg/mL in Bonin-Jacob et al. study (Bonin-Jacob et al. 2021), and in our study that in cervical cancer patients was 9.05 (3.79–26.48) pg/mL, it decreased significantly to 4.79 (2.35–8.68) pg/mL after radical hysterectomy and increased slightly to 6.83 (4.21–12.42) pg/mL at the relapse phase. This evidence concerns the gene IL6 and cervical cancer.