HLA-G and cervical cancer: Based on these results, the following models for immune escape of cervical cancer cells can be hypothesised: following the HPV infection, sHLA-G expression may be induced and shift the cytokines expression profile towards Th2 in the peripheral blood circulation (Viganò et al. 2003; Xu et al. 2020; Almeida et al. 2018; Carosella et al. 2011); this in turn may further promote immunosuppression by upregulating HLA-G expression, including DC-10s, Treg, and MDSCs (Liang et al. 2008; Gregori et al. 2010; Xu et al. 2016; Naji et al. 2007; Urosevic and Dummer 2003; Pistoia et al. 2007).