Feeding UHT induced subclinical changes in the immature gut of the preterm pigs such as impaired lactase activity, activated innate immune responses and stunted villi, and feeding SUHT further caused accumulation of MRPs and an increase in expression of AGEs receptor in the intestine accompanied by clinical symptoms with more diarrhea, more severe NEC, a more pronounced inflammatory response, and functional and morphological damages relative to PAST (Figure 2). This evidence concerns the gene LCT and necrotizing enterocolitis.