12 proteins (ATP5F1B, CALML5, PSMD2, PSMB4, PPP3CB, SLC39A10, SLC39A10, SLC25A4, SLC25A5, TUBB4A, TUBA1A, VDAC1) are co-exist in pathways of the above four neurological disease; this suggests that there may be a common mechanism between these neurological diseases and hydrocephalus in BM. The gene discussed is TUBA1A; the disease is nervous system disorder.