C1QTNF6 and ischemic stroke: Considering the pathological role of inflammation in ischemic stroke and the abnormal expression of miR-29b and C1QTNF6 in leukocytes of ischemic stroke patients, this study hypothesizes that miR-29b in peripheral leukocytes participates in the inflammatory response by targeting C1QTNF6 and degrading the integrity of the BBB after ischemic stroke.