Although VDAC1 is also differentially expressed by apoptotic regulation (62), we propose that the approximately 27% (r2 squared Pearson) of VDAC1 variation among the lung cancer biopsies, which was explained by EPOR expression, reflects differences in mitochondrial content (44, 61, 63, 64). The gene discussed is VDAC1; the disease is lung carcinoma.