HuR is a tumor maintenance gene that allows malignant transformation, tumor growth and metastasis of RBPs.HuR binds to the 3’UTR of many proto-oncogenes and unstable AREs to regulate the stability and enhance the translation of target mRNAs, and it is also a key regulator affecting their translocation from the nucleus to the cytoplasm (87). The gene discussed is ELAVL1; the disease is neoplasm.