TTP, an RNA-binding protein 1 and KH-type splicing regulatory protein that normally promotes mRNA degradation, reduces the half-life of VEGF mRNA and slows the growth of RAS-transformed cell-derived nude mouse xenograft tumors, in turn reducing the microvessel density in tumors and leading to the inhibition of tumor growth and angiogenesis (118). Here, VEGFA is linked to neoplasm.