A higher percentage of MMP14-expressing cells among CAFs (MMP14+ CAF/CAF ratio) was associated with a poorer RFS (HR of 1.936, with a 95% CI of 0.855–4.384), whereas a similar trend was not apparent for MMP14 expression in tumor cells, TAMs, or TILs (Figure 3B and Supplementary Figure S3A). This evidence concerns the gene MMP14 and neoplasm.