The immune scores (R = 0.31, p = 1.3e-09), stromal scores (R = 0.36, p = 1.4e-12), and ESITIMAT scores (R = 0.35, p = 4.1e-12) showed a significantly positive correlation with EFNB1 expression, while EFNB1 expression was negatively correlated with tumor purity (R = −0.35, p = 4.1e-12) in HCC (Figures 6I–L). This evidence concerns the gene EFNB1 and neoplasm.