Similarly, HCC patients with high MSI exhibited higher EFNA3 (p = 0.0046) and EFNA4 (p = 0.004) expression than those with low MSI (Figures 9G,H), and the expression levels of EFNA3 (R = 0.14, p = 0.0075) and EFNA4 (R = 0.15, p = 0.003) were significantly positively related to MSI scores based on Spearman correlation analysis (Figures 9J,K). The gene discussed is EFNA3; the disease is hepatocellular carcinoma.