The mRNA expression of EFNA2 in tumor tissues of GBM, LGG, UCEC, BRCA, CESC, LUAD, ESCA, STES, KIRP, COAD, PRAD, STAD, KIRC, LUSC, WT, SKCM, BLCA, THCA, OV, PAAD, TGCT, UCS, ALL, LAML, PCPG, and ACC was higher than that in corresponding normal tissues. The gene discussed is EFNA2; the disease is glioblastoma.