EFNA4 and hepatocellular carcinoma: We found that HCC patients with a high TMB highly expressed EFNA3 (p = 0.046) and EFNA4 (p = 0.048) (Figures 9A,B), and Spearman correlation analysis also indicated that TMB levels were positively correlated with the expression of EFNA3 (R = 0.13, p = 0.015) and EFNA4 (R = 0.15, p = 0.0039) (Figures 9D,E).