PTCH1 and basal cell carcinoma: Gorlin syndrome, or nevoid basal cell carcinoma syndrome (NBCCS), is an autosomal dominant syndrome caused by mutations in the PTCH1 (Patched 1) gene, characterized by multiple basal cell carcinomas (BCCs) occurring from puberty, in addition to various dental, osseous, ophthalmic, neurological, and sex organ abnormalities (Jawa et al., 2009).