Bai et al. (2018a) found that Tet induced autophagy and apoptosis in human gastric cancer cells by inducing autophagy and apoptosis involving the Akt/mTOR pathway. Tet inhibited the proliferation of MDA-MB-231 cells and induced autophagy by inhibiting the PI3K/AKT/mTOR pathway (Guo and Pei, 2019). This evidence concerns the gene AKT1 and gastric cancer.