According to the data from the TCGA platform, we found the downregulation of FAT4 expression in 14 types of cancer, including BLCA, BRCA, COAD, KICH, KIRP, LIHC, LUAD, LUSC, PRAD, READ, THCA, UCEC, CESC, and GBM. This evidence concerns the gene FAT4 and cancer.