In summary, FAT4 is abnormally downregulated in 14 types of cancer, including BLCA, BRCA, COAD, KICH, KIRP, LIHC, LUAD, LUSC, PRAD, READ, THCA, UCEC, CESC, and GBM tumor tissues, and its anomalous expression is related to the prognosis of tumors. This evidence concerns the gene FAT4 and glioblastoma.