Moreover, Th1 cells, Th17 cells, ILC1s, ILC3s, and M1 macrophages are involved in this endotype, and their production IL‐1β, IL‐6, IL‐17, IFN‐γ, and TNF‐α are responsible for the recruitment and activation of inflammatory cells during asthma attacks. This evidence concerns the gene IL6 and asthma.