LPL and hyperinsulinemic hypoglycemia, familial, 4: Patients with GPIHBP1 deficiency express a similar phenotype as patients with LPL deficiency, such as severe chylomicronemia (plasma TG levels above 1,500 mg/dl (16.9 mmol/L) presented already in childhood and high risk of pancreatitis (Miyashita et al., 2020).