The following were significantly different between the anxiety disorder with CHD group and the simple anxiety disorder group: sex (P = 0.004), age (P = 0.031), smoking status (P = 0.005), diabetes mellitus (P = 0.008), hypertension (P = 0.005), and IL-6 levels (P < 0.001), hs-CRP (P < 0.001), and Hcy (P < 0.001); the other variables have no change (Table 2). The gene discussed is IL6; the disease is coronary artery disorder.