Of note, we also did not detect any CD4+ “helper” T lymphocytes or CD4+ Foxp3+ “regulatory” T-cells in the pre-malignant SVZ regions of our models, accurately representing the low density of these populations in the scRNA-seq analyses of established GBM tumors we recently reported (Zamler et al., 2022). This evidence concerns the gene FOXP3 and glioblastoma.