QKI and glioblastoma: Three neighboring genes residing this locus are PRKN (PARKIN), PACRG (Parkin Coregulated Gene), and QKI (QUAKING), and both PRKN and QKI have been shown to be tumor suppressors in GBM (Gilbert, 2002; Brennan et al., 2013; Darbelli and Richard, 2016; de Castro et al., 2021).