In the light of the novel molecular classifications of DLBCL using the Chapuy [5] and Schmitz [4] models, two molecular patterns are enriched particularly in PE‐DLBCLs: the “cluster 5” or “MCD‐type” based on MYD88 and CD79B mutations and the “cluster 2” or “BN‐2” type, based on BCL6 fusions and NOTCH2 mutations, which are associated with MALT lymphomas. Here, MYD88 is linked to diffuse large B-cell lymphoma.