Our approach is also able to recognize a higher proportion of DLBCL cases that fail to respond to R‐CHOP than reported in recent published articles that have identified either a high‐grade DLBCL subclass that is limited to the GCB group [53], or 9% of DLBCL cases with poor prognosis [54]. The gene discussed is DDIT3; the disease is diffuse large B-cell lymphoma.