The most notable translocations involving MYC and IG loci in DLBCL include t(8;14)(q24;q32) leading to a MYC and IG heavy chain fusion (MYC‐IGH), t(8;22)(q24;q11) resulting in a MYC‐IGL (lamda light chain) fusion and the less common, t(2;8)(p12;q24) that results in a MYC‐IGK (kappa light chain) fusion with frequencies of 70%, 22%, and 8% respectively [5, 6]. This evidence concerns the gene MYC and diffuse large B-cell lymphoma.