By comparing colonic mRNA levels of various BARs in colitis animals, most BARs levels were increased in PCDSS mice (Figure S5a), such as Gpbar1(TGR5), Vdr, Nr1h3 (LXRα), Nr1h2 (LXRβ), Nr1i2 (PXR), and Nr1i3 (CAR). The gene discussed is NR1H2; the disease is colitis.