CD4 and autoimmune thrombocytopenic purpura: Representative dot plots of Th1, Th2, Tregs, Th17, CD4 + TNFα + , and CD4 + TGFβ + cells in the PBMCs of HC, positive pathogen-ITP patient, and negative pathogen-ITP patient were shown in Fig. 3A, B, C, D, E and F. The percentages of Th1 cells (Fig. 3G) and CD4+ TNFα+ cells (Fig. 3K) were decreased significantly in positive pathogen-ITP and negative pathogen-ITP patients, as compared to HC (p < 0.05).