SATB2 and rheumatoid arthritis: To test whether miR-338-3p directly targets the 3'UTR of GLSs, we tested the expression of GLSs in the wild-type or binding site mutant 3'UTR containing Luciferase reporter assays were performed by co-transfection of luciferase vectors and control miRNAs or miR-338-3p into normal FLSs and FLSs-RA.