Pezzullo et al. [18] reported an increased incidence of CMV reactivation in older adults (age > 60 years) with non-HL who were treated with bendamustine-containing regimens, especially after the third course of bendamustine accompanied by a significant depression of circulating CD4-positive T cell count and anti-CMV IgG levels. Here, CD4 is linked to Hodgkins lymphoma.