CD8A and neoplasm: Treatment of LNCaP cells with SGI and LBH in combination significantly increased the percent of PSMA+CD8+ T-cells after co-culture with LNCaP cells at a 2:1 or 1:1 T-cell effector to tumor target (E:T) ratio SGI alone was able to significantly increase the percent of PSMA+CD8+ T-cells after co-culture with LNCaP cells at a 2:1 or 1:1 T-cell effector to tumor target ratio.