Using Gene Expression Profile Interaction Analysis (GEPIA), we found that upregulation of ANGPTL4 predicted the poor prognosis in patients of lung adenocarcinoma (LUAD) (Fig. 1b) as well as adrenocortical carcinoma (ACC), stomach adenocarcinoma (STAD) and brain lower grade glioma (LGG) (Supplementary Fig. s1), suggesting that ANGPTL4 has a potential to be a therapeutic target. The gene discussed is ANGPTL4; the disease is lung adenocarcinoma.