ANGPTL4 and non-small cell lung carcinoma: Given that ANGPTL4 was expressed at a low background level under normoxic condition, we transfected NSCLC cells with ANGPTL4-OE lentivirus under normoxia and sh-ANGPTL4 lentivirus under hypoxia to investigate the biological functions of hypoxia-induced-ANGPTL4 in a positive or negative manner.