To further explore the function of ANGPTL4 in hypoxic tumour radioresistance, the cells stably transfected with lentivirus-mediated ANGPTL4 interference (sh-ANGPTL4) and overexpression (ANGPTL4-OE) were constructed and verified by qRT-PCR and Western blot assay, respectively (Fig. 2a, b and Supplementary Fig. s2). The gene discussed is ANGPTL4; the disease is neoplasm.