MRE11 and endometrial endometrioid adenocarcinoma: The MRE11 K255E mutation, in particular, has been identified in uterine endometrioid carcinoma (1/399, in cBioPortal database), and both K255E and K384Q/I mutations have been found in hereditary cancer-predisposing syndrome, but their intrinsic effect on cancer development is still unknown.