ABCC8 and hypertrophy: Candidate genes common to QT and JT within insulin related pathways include SLC2A4, PIGQ, and ABCC8. SLC2A4 (alias GLUT4), is a glucose transporter in cardiomyocytes with effects on cardiac contractility, development of hypertrophy, and susceptibility to atrial and ventricular arrhythmias46–48.