Accordingly, high JMJD5 expression indicated a good prognosis in breast cancer, hepatocellular carcinoma, and lung cancer but a poor prognosis in stomach adenocarcinoma.161 In this study, JMJD5 expression was also related to the abundance of infiltrating immune cells in tumors, which might jointly serve as a prognostic marker. This evidence concerns the gene KDM8 and lung cancer.