PDC and stroke disorder: We found no evidence (at P < 0.05) for increased odds of CAD [OR (95% CI) = 1.06 (0.84, 1.35)], MI [OR (95% CI) = 1.02 (0.79, 1.33)] or stroke [OR (95% CI) = 0.91 (0.66, 1.24)] for a 1-unit increase in Hgb level in the physiological range (e.g. from 14.2 to 15.2 g/dl) through genetically proxied PHD inhibition (Fig. 1, Supplementary Material, Table S5).