LIN was one of seven classes of IGF1R/IR inhibitors disclosed before 2012.43 When LIN’s intramacrophage anti-TB activity was to be examined, Av-Gay and co-workers published the results of a high-content screening for kinase inhibition that could enable intracellular killing of Mtb.25 LIN was one of the kinase inhibitors included in the screening. This evidence concerns the gene INSR and tuberculosis.