IGF1R and tuberculosis: LIN was one of seven classes of IGF1R/IR inhibitors disclosed before 2012.43 When LIN’s intramacrophage anti-TB activity was to be examined, Av-Gay and co-workers published the results of a high-content screening for kinase inhibition that could enable intracellular killing of Mtb.25 LIN was one of the kinase inhibitors included in the screening.