HM13 and rectum adenocarcinoma: RNA-seq data from TCGA showed that HM13 mRNA expression was up-regulated in several tumor tissues, including uterine corpus endometrial carcinoma (UCEC), cholangio carcinoma (CHOL), glioblastoma multiforme (GBM), breast invasive carcinoma (BRCA), KIRC, HNSC, LIHC, KIRP, lung squamous cell carcinoma (LUSC), lung adenocarcinoma (LUAD), bladder urothelial carcinoma (BLCA), colon adenocarcinoma (COAD), esophageal carcinoma (ESCA), prostate adenocarcinoma (PRAD), stomach adenocarcinoma (STAD), and rectum adenocarcinoma (READ) (Figure 1A).